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Apelin receptor homodimer-oligomers revealed by single-molecule imaging and novel G protein-dependent signaling
The apelin receptor (APJ) belongs to family A of the G protein-coupled receptors (GPCRs) and is a potential pharmacotherapeutic target for heart failure, hypertension, and other cardiovascular diseases. There is evidence APJ heterodimerizes with other GPCRs; however, the existence of APJ homodimers...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5238433/ https://ncbi.nlm.nih.gov/pubmed/28091541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40335 |
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