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Identification of Serine 348 on the Apelin Receptor as a Novel Regulatory Phosphorylation Site in Apelin-13-induced G Protein-independent Biased Signaling

Phosphorylation plays vital roles in the regulation of G protein-coupled receptor (GPCR) functions. The apelin and apelin receptor (APJ) system is involved in the regulation of cardiovascular function and central control of body homeostasis. Here, using tandem mass spectrometry, we first identified...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Chen, Xiaoyu, Bai, Bo, Tian, Yanjun, Du, Hui, Chen, Jing
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223320/
https://ncbi.nlm.nih.gov/pubmed/25271156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574020
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