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Identification of Serine 348 on the Apelin Receptor as a Novel Regulatory Phosphorylation Site in Apelin-13-induced G Protein-independent Biased Signaling

Phosphorylation plays vital roles in the regulation of G protein-coupled receptor (GPCR) functions. The apelin and apelin receptor (APJ) system is involved in the regulation of cardiovascular function and central control of body homeostasis. Here, using tandem mass spectrometry, we first identified...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chen, Xiaoyu, Bai, Bo, Tian, Yanjun, Du, Hui, Chen, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223320/
https://ncbi.nlm.nih.gov/pubmed/25271156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574020
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