The Effects of Apelin and Elabela Ligands on Apelin Receptor Distinct Signaling Profiles

Apelin and Elabela are endogenous peptide ligands for Apelin receptor (APJ), a widely expressed G protein-coupled receptor. They constitute a spatiotemporal dual ligand system to control APJ signal transduction and function. We investigated the effects of Apelin-13, pGlu(1)-apelin-13, Apelin-17, Ape...

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Publicado en:Front Pharmacol
Autores principales: Jiang, Yunlu, Yan, Maocai, Wang, Chunmei, Wang, Qinqin, Chen, Xiaoyu, Zhang, Rumin, Wan, Lei, Ji, Bingyuan, Dong, Bo, Wang, Huiyun, Chen, Jing
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970304/
https://ncbi.nlm.nih.gov/pubmed/33746758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.630548
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