Characterization of a programmed alteration in an 18S ribosomal gene that accompanies the experimental induction of drug resistance in Schistosoma mansoni.

Stable resistance to the anthelmintic hycanthone can be produced in the human blood fluke Schistosoma mansoni by exposing immature parasites in mice to the drug. Within a single generation, genomic rearrangements, detected as rRNA-encoding DNA restriction fragment length polymorphisms (RFLPs), accom...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Brindley, P J, Heath, S, Waters, A P, McCutchan, T F, Sher, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52381/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1679236/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.17.7754
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!