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Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.

In previous studies, we utilized a neutral/neutral two-dimensional (2-D) gel replicon mapping method to analyze the pattern of DNA synthesis in the amplified dihydrofolate reductase (DHFR) domain of CHOC 400 cells. Replication forks appeared to initiate at any of a large number of sites scattered th...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Dijkwel, P A, Vaughn, J P, Hamlin, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1994
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC523768/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7800491/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.23.4989
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