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Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.

In previous studies, we utilized a neutral/neutral two-dimensional (2-D) gel replicon mapping method to analyze the pattern of DNA synthesis in the amplified dihydrofolate reductase (DHFR) domain of CHOC 400 cells. Replication forks appeared to initiate at any of a large number of sites scattered th...

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Autors principals: Dijkwel, P A, Vaughn, J P, Hamlin, J L
Format: Artigo
Idioma:Inglês
Publicat: 1994
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC523768/
https://ncbi.nlm.nih.gov/pubmed/7800491
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