Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.
In previous studies, we utilized a neutral/neutral two-dimensional (2-D) gel replicon mapping method to analyze the pattern of DNA synthesis in the amplified dihydrofolate reductase (DHFR) domain of CHOC 400 cells. Replication forks appeared to initiate at any of a large number of sites scattered th...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1994
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC523768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7800491/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.23.4989 |
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