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Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.
In previous studies, we utilized a neutral/neutral two-dimensional (2-D) gel replicon mapping method to analyze the pattern of DNA synthesis in the amplified dihydrofolate reductase (DHFR) domain of CHOC 400 cells. Replication forks appeared to initiate at any of a large number of sites scattered th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1994
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC523768/ https://ncbi.nlm.nih.gov/pubmed/7800491 |
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