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Force regulated conformational change of integrin α(V)β(3)
Integrins mediate cell adhesion to extracellular matrix and transduce signals bidirectionally across the membrane. Integrin α(V)β(3) has been shown to play an essential role in tumor metastasis, angiogenesis, hemostasis and phagocytosis. Integrins can take several conformations, including the bent a...
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| Publicado no: | Matrix Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5237428/ https://ncbi.nlm.nih.gov/pubmed/27423389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.07.002 |
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