Á lódáil...
Structural Basis and Kinetics of Force-Induced Conformational Changes of an αA Domain-Containing Integrin
BACKGROUND: Integrin α(L)β(2) (lymphocyte function-associated antigen, LFA-1) bears force upon binding to its ligand intercellular adhesion molecule 1 (ICAM-1) when a leukocyte adheres to vascular endothelium or an antigen presenting cell (APC) during immune responses. The ligand binding propensity...
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Main Authors: | , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Public Library of Science
2011
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225382/ https://ncbi.nlm.nih.gov/pubmed/22140490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027946 |
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