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Activated αvβ3 Integrin Regulates αvβ5 Integrin–Mediated Phagocytosis in Trabecular Meshwork Cells

PURPOSE. To investigate the roles of αvβ3 and αvβ5 integrins in phagocytosis in human trabecular meshwork (HTM) cells. METHODS. Immunofluorescence microscopy and FACS analysis were used to determine levels of αvβ3 and αvβ5 integrins in TM tissue and cultures of normal and immortalized TM cells. Phag...

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Detalhes bibliográficos
Main Authors: Gagen, Debjani, Filla, Mark S., Clark, Ross, Liton, Paloma, Peters, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723377/
https://ncbi.nlm.nih.gov/pubmed/23821196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12084
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