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Mechanisms of mutagenesis: DNA replication in the presence of DNA damage

Environmental mutagens cause DNA damage that disturbs replication and produces mutations, leading to cancer and other diseases. We discuss mechanisms of mutagenesis resulting from DNA damage, from the level of DNA replication by a single polymerase to the complex DNA replisome of some typical model...

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Dades bibliogràfiques
Publicat a:Mutat Res Rev Mutat Res
Autors principals: Liu, Binyan, Xue, Qizhen, Tang, Yong, Cao, Jia, Guengerich, F. Peter, Zhang, Huidong
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237373/
https://ncbi.nlm.nih.gov/pubmed/27234563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2016.03.006
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