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CNV instability associated with DNA replication dynamics: evidence for replicative mechanisms in CNV mutagenesis
Copy number variation (CNV) in the human genome is of vital importance to human health and evolution of our species. However, much of the molecular basis of CNV mutagenesis remains to be elucidated. Considering the DNA replication model of ‘fork stalling and template switching’ for CNV formation, we...
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| Publicat a: | Hum Mol Genet |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381758/ https://ncbi.nlm.nih.gov/pubmed/25398944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu572 |
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