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Increased genome instability in human DNA segments with self-chains: homology-induced structural variations via replicative mechanisms

Environmental factors including ionizing radiation and chemical agents have been known to be able to induce DNA rearrangements and cause genomic structural variations (SVs); however, the roles of intrinsic characteristics of the human genome, such as regional genome architecture, in SV formation and...

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Bibliografiske detaljer
Main Authors: Zhou, Weichen, Zhang, Feng, Chen, Xiaoli, Shen, Yiping, Lupski, James R., Jin, Li
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674805/
https://ncbi.nlm.nih.gov/pubmed/23474816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt113
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