Human endogenous retroviral elements promote genome instability via non-allelic homologous recombination

BACKGROUND: Recurrent rearrangements of the human genome resulting in disease or variation are mainly mediated by non-allelic homologous recombination (NAHR) between low-copy repeats. However, other genomic structures, including AT-rich palindromes and retroviruses, have also been reported to underl...

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Detalhes bibliográficos
Main Authors: Campbell, Ian M, Gambin, Tomasz, Dittwald, Piotr, Beck, Christine R, Shuvarikov, Andrey, Hixson, Patricia, Patel, Ankita, Gambin, Anna, Shaw, Chad A, Rosenfeld, Jill A, Stankiewicz, Paweł
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195946/
https://ncbi.nlm.nih.gov/pubmed/25246103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-014-0074-4
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