Kinetic analysis of bypass of 7,8-dihydro-8-oxo-2′-deoxyguanosine by the catalytic core of yeast DNA polymerase η

Reactive oxygen species damage DNA bases to produce 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-oxoG), which results in G:C to T:A transversions. To better understand mechanisms of dNTP incorporation opposite 8-oxoG, we performed pre-steady-state kinetic analysis of nucleotide incorporation using the cat...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Biochimie
Asıl Yazarlar: Xue, Qizhen, Zhong, Mengyu, Liu, Binyan, Tang, Yong, Wei, Zeliang, Guengerich, F. Peter, Zhang, Huidong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193378/
https://ncbi.nlm.nih.gov/pubmed/26700143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2015.12.009
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller