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Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences.
Conventionally designed ribozymes may be unable to cleave RNA at sites which are inaccessible due to secondary structure. In addition, it may also be difficult to specifically target a conventionally designed ribozyme to some chimeric RNA molecules. Novel approaches for ribozyme targeting were devel...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1994
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC523580/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.3.301 |
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