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Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences.
Conventionally designed ribozymes may be unable to cleave RNA at sites which are inaccessible due to secondary structure. In addition, it may also be difficult to specifically target a conventionally designed ribozyme to some chimeric RNA molecules. Novel approaches for ribozyme targeting were devel...
Kaydedildi:
| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
1994
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| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC523580/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.3.301 |
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