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Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins.

Chronic myelogenous leukemia and one type of acute lymphoblastic leukemia are characterized by a 9;22 chronosome translocation in which 5' sequences of the bcr gene become fused to the c-abl proto-oncogene. The resulting chimeric genes encode bcr/abl fusion proteins which have deregulated tyros...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell Biol
主要な著者: McWhirter, J R, Wang, J Y
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369443/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.3.1553
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