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Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences.

Conventionally designed ribozymes may be unable to cleave RNA at sites which are inaccessible due to secondary structure. In addition, it may also be difficult to specifically target a conventionally designed ribozyme to some chimeric RNA molecules. Novel approaches for ribozyme targeting were devel...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Pachuk, C J, Yoon, K, Moelling, K, Coney, L R
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1994
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC523580/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.3.301
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