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Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling
Toll-like receptor (TLR) activation is central to immunity, wherein the activation of the TLR9 subfamily members TLR9 and TLR7 results in the robust induction of type I IFNs (IFN-α/β) by means of the MyD88 adaptor protein. However, it remains unknown how the TLR signal “input” can be processed throu...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC523464/ https://ncbi.nlm.nih.gov/pubmed/15492225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406933101 |
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