Bacteriolytic therapy can generate a potent immune response against experimental tumors

When spores of the anaerobic bacterium Clostridium novyi-NT are systemically injected into animals, they germinate exclusively within the hypoxic regions of cancers. The germinated bacteria destroy adjacent tumor cells but spare a rim of well oxygenated tumor cells that subsequently expand. Surprisi...

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Dades bibliogràfiques
Autors principals: Agrawal, Nishant, Bettegowda, Chetan, Cheong, Ian, Geschwind, Jean-Francois, Drake, Charles G., Hipkiss, Edward L., Tatsumi, Mitsuaki, Dang, Long H., Diaz, Luis A., Pomper, Martin, Abusedera, Mohammad, Wahl, Richard L., Kinzler, Kenneth W., Zhou, Shibin, Huso, David L., Vogelstein, Bert
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC523456/
https://ncbi.nlm.nih.gov/pubmed/15471990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406242101
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