Bacteriolytic therapy can generate a potent immune response against experimental tumors

When spores of the anaerobic bacterium Clostridium novyi-NT are systemically injected into animals, they germinate exclusively within the hypoxic regions of cancers. The germinated bacteria destroy adjacent tumor cells but spare a rim of well oxygenated tumor cells that subsequently expand. Surprisi...

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Библиографические подробности
Главные авторы: Agrawal, Nishant, Bettegowda, Chetan, Cheong, Ian, Geschwind, Jean-Francois, Drake, Charles G., Hipkiss, Edward L., Tatsumi, Mitsuaki, Dang, Long H., Diaz, Luis A., Pomper, Martin, Abusedera, Mohammad, Wahl, Richard L., Kinzler, Kenneth W., Zhou, Shibin, Huso, David L., Vogelstein, Bert
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC523456/
https://ncbi.nlm.nih.gov/pubmed/15471990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406242101
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