Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria

The low level of oxygenation within tumors is a major cause of radiation treatment failures. We theorized that anaerobic bacteria that can selectively destroy the hypoxic regions of tumors would enhance the effects of radiation. To test this hypothesis, we used spores of Clostridium novyi-NT to trea...

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Detalhes bibliográficos
Main Authors: Bettegowda, Chetan, Dang, Long H., Abrams, Ross, Huso, David L., Dillehay, Larry, Cheong, Ian, Agrawal, Nishant, Borzillary, Scott, McCaffery, J. Michael, Watson, E. Latice, Lin, Kuo-Shyan, Bunz, Fred, Baidoo, Kwamena, Pomper, Martin G., Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299912/
https://ncbi.nlm.nih.gov/pubmed/14657371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2036598100
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