Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria

The low level of oxygenation within tumors is a major cause of radiation treatment failures. We theorized that anaerobic bacteria that can selectively destroy the hypoxic regions of tumors would enhance the effects of radiation. To test this hypothesis, we used spores of Clostridium novyi-NT to trea...

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Bibliografiska uppgifter
Huvudupphovsmän: Bettegowda, Chetan, Dang, Long H., Abrams, Ross, Huso, David L., Dillehay, Larry, Cheong, Ian, Agrawal, Nishant, Borzillary, Scott, McCaffery, J. Michael, Watson, E. Latice, Lin, Kuo-Shyan, Bunz, Fred, Baidoo, Kwamena, Pomper, Martin G., Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2003
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC299912/
https://ncbi.nlm.nih.gov/pubmed/14657371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2036598100
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