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Non-small cell lung cancer (NSCLC) and central nervous system (CNS) metastases: role of tyrosine kinase inhibitors (TKIs) and evidence in favor or against their use with concurrent cranial radiotherapy

Central nervous system (CNS) metastases, including brain metastases (BM) and leptomeningeal metastases (LM) represent a frequent complication of non-small cell lung cancer (NSCLC). Patients with BM comprise a heterogeneous group, with a median survival that ranges from 3 to 14 months. However, in th...

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Publicat a:Transl Lung Cancer Res
Autors principals: Economopoulou, Panagiota, Mountzios, Giannis
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233883/
https://ncbi.nlm.nih.gov/pubmed/28149754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2016.12.06
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