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Achievements and future developments of ALK-TKIs in the management of CNS metastases from ALK-positive NSCLC

Non-small cell lung cancer (NSCLC) represents the paradigm of personalized treatment of human cancer. Several oncogenic druggable alterations have been so far identified, with anaplastic lymphoma kinase (ALK) gene rearrangements being one of the newest and most appealing. Presence of ALK fusions is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transl Lung Cancer Res
Hauptverfasser: Landi, Lorenza, Cappuzzo, Federico
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233871/
https://ncbi.nlm.nih.gov/pubmed/28149753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2016.12.05
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