Non-small cell lung cancer (NSCLC) and central nervous system (CNS) metastases: role of tyrosine kinase inhibitors (TKIs) and evidence in favor or against their use with concurrent cranial radiotherapy

Central nervous system (CNS) metastases, including brain metastases (BM) and leptomeningeal metastases (LM) represent a frequent complication of non-small cell lung cancer (NSCLC). Patients with BM comprise a heterogeneous group, with a median survival that ranges from 3 to 14 months. However, in th...

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Detalles Bibliográficos
Publicado en:Transl Lung Cancer Res
Main Authors: Economopoulou, Panagiota, Mountzios, Giannis
Formato: Artigo
Idioma:Inglês
Publicado: AME Publishing Company 2016
Assuntos:
Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233883/
https://ncbi.nlm.nih.gov/pubmed/28149754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2016.12.06
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