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Making progress in epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer by surpassing resistance: third-generation EGFR tyrosine kinase inhibitors (EGFR-TKIs)

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) represent the standard of care for advanced non-small cell lung cancer (NSCLC) patients whose tumours harbor an activating EGFR mutation. Unfortunately, resistance to first- and second-generation EGFR-TKIs inevitably occurs in a...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Autor principal: Mountzios, Giannis
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952013/
https://ncbi.nlm.nih.gov/pubmed/29862229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2017.10.04
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