ロード中...

Design and synthesis of a specific endothelin 1 antagonist: effects on pulmonary vasoconstriction.

The 21-amino acid vasoconstrictor peptide endothelin (Et) contains two disulfide bonds. We investigated the importance of the outer disulfide bond in Et-1 by replacing it with an amide linkage. Bioactivity was assessed in an isolated guinea pig lung preparation (perfused at constant flow with Ringer...

詳細記述

保存先:
書誌詳細
主要な著者: Spinella, M J, Malik, A B, Everitt, J, Andersen, T T
フォーマット: Artigo
言語:Inglês
出版事項: 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC52312/
https://ncbi.nlm.nih.gov/pubmed/1871142
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!