The Protective Effect of the Mycobacterium bovis BCG Vaccine Is Increased by Coadministration with the Mycobacterium tuberculosis 72-Kilodalton Fusion Polyprotein Mtb72F in M. tuberculosis-Infected Guinea Pigs

A tuberculosis vaccine candidate consisting of a 72-kDa polyprotein or fusion protein based upon the Mtb32 and Mtb39 antigens of Mycobacterium tuberculosis and designated Mtb72F was tested for its protective capacity as a potential adjunct to the Mycobacterium bovis BCG vaccine in the mouse and guin...

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Bibliographische Detailangaben
Hauptverfasser: Brandt, Lise, Skeiky, Yasir A. W., Alderson, Mark R., Lobet, Yves, Dalemans, Wilfried, Turner, Oliver C., Basaraba, Randall J., Izzo, Angelo A., Lasco, Todd M., Chapman, Philip L., Reed, Steven G., Orme, Ian M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC523007/
https://ncbi.nlm.nih.gov/pubmed/15501795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6622-6632.2004
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