The Protective Effect of the Mycobacterium bovis BCG Vaccine Is Increased by Coadministration with the Mycobacterium tuberculosis 72-Kilodalton Fusion Polyprotein Mtb72F in M. tuberculosis-Infected Guinea Pigs

A tuberculosis vaccine candidate consisting of a 72-kDa polyprotein or fusion protein based upon the Mtb32 and Mtb39 antigens of Mycobacterium tuberculosis and designated Mtb72F was tested for its protective capacity as a potential adjunct to the Mycobacterium bovis BCG vaccine in the mouse and guin...

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Autors principals: Brandt, Lise, Skeiky, Yasir A. W., Alderson, Mark R., Lobet, Yves, Dalemans, Wilfried, Turner, Oliver C., Basaraba, Randall J., Izzo, Angelo A., Lasco, Todd M., Chapman, Philip L., Reed, Steven G., Orme, Ian M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC523007/
https://ncbi.nlm.nih.gov/pubmed/15501795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6622-6632.2004
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