Evaluation of the Mtb72F Polyprotein Vaccine in a Rabbit Model of Tuberculous Meningitis

Using a rabbit model of tuberculous meningitis, we evaluated the protective efficacy of vaccination with the recombinant polyprotein Mtb72F, which is formulated in two alternative adjuvants, AS02A and AS01B, and compared this to vaccination with Mycobacterium bovis bacillus Calmette-Guérin (BCG) alo...

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Detalhes bibliográficos
Main Authors: Tsenova, Liana, Harbacheuski, Ryhor, Moreira, Andre L., Ellison, Evette, Dalemans, Wilfried, Alderson, Mark R., Mathema, Barun, Reed, Steven G., Skeiky, Yasir A. W., Kaplan, Gilla
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418915/
https://ncbi.nlm.nih.gov/pubmed/16552069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2392-2401.2006
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