Tracking Antigen-Specific CD8 T Lymphocytes in the Lungs of Mice Vaccinated with the Mtb72F Polyprotein

This study used a major histocompatibility complex class I tetramer reagent to track antigen-specific CD8 T cells in the lungs of mice immunized with the tuberculosis vaccine candidate Mtb72F. The results show that CD8 T cells recognizing an immunodominant Mtb32-specific epitope could be detected in...

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Detalhes bibliográficos
Main Authors: Irwin, Scott M., Izzo, Angelo A., Dow, Steven W., Skeiky, Y. A. W., Reed, Steven G., Alderson, Mark R., Orme, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231129/
https://ncbi.nlm.nih.gov/pubmed/16113299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5809-5816.2005
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