Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

The development of a vaccine for tuberculosis requires a combination of antigens and adjuvants capable of inducing appropriate and long-lasting T cell immunity. We evaluated Mtb72F formulated in AS02A in the cynomolgus monkey model. The vaccine was immunogenic and caused no adverse reactions. When m...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Reed, Steven G., Coler, Rhea N., Dalemans, Wilfried, Tan, Esterlina V., DeLa Cruz, Eduardo C., Basaraba, Randall J., Orme, Ian M., Skeiky, Yasir A. W., Alderson, Mark R., Cowgill, Karen D., Prieels, Jean-Paul, Abalos, Rodolfo M., Dubois, Marie-Claude, Cohen, Joe, Mettens, Pascal, Lobet, Yves
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650151/
https://ncbi.nlm.nih.gov/pubmed/19188599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712077106
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi