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Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys
The development of a vaccine for tuberculosis requires a combination of antigens and adjuvants capable of inducing appropriate and long-lasting T cell immunity. We evaluated Mtb72F formulated in AS02A in the cynomolgus monkey model. The vaccine was immunogenic and caused no adverse reactions. When m...
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| Autori principali: | , , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650151/ https://ncbi.nlm.nih.gov/pubmed/19188599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712077106 |
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