Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

The development of a vaccine for tuberculosis requires a combination of antigens and adjuvants capable of inducing appropriate and long-lasting T cell immunity. We evaluated Mtb72F formulated in AS02A in the cynomolgus monkey model. The vaccine was immunogenic and caused no adverse reactions. When m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Reed, Steven G., Coler, Rhea N., Dalemans, Wilfried, Tan, Esterlina V., DeLa Cruz, Eduardo C., Basaraba, Randall J., Orme, Ian M., Skeiky, Yasir A. W., Alderson, Mark R., Cowgill, Karen D., Prieels, Jean-Paul, Abalos, Rodolfo M., Dubois, Marie-Claude, Cohen, Joe, Mettens, Pascal, Lobet, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650151/
https://ncbi.nlm.nih.gov/pubmed/19188599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712077106
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados