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DNA-Catalyzed DNA Cleavage by a Radical Pathway with Well-Defined Products
We describe an unprecedented DNA-catalyzed DNA cleavage process in which a radical-based reaction pathway cleanly results in excision of most atoms of a specific guanosine nucleoside. Two new deoxyribozymes (DNA enzymes) were identified by in vitro selection from N(40) or N(100) random pools initial...
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| Udgivet i: | J Am Chem Soc |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5226912/ https://ncbi.nlm.nih.gov/pubmed/27935689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10274 |
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