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DNA-catalyzed glycosylation using aryl glycoside donors()

We report the identification by in vitro selection of Zn(2+)/Mn(2+)-dependent deoxyribozymes that glycosylate the 3′-OH of a DNA oligonucleotide. Both β and α anomers of aryl glycosides can be used as the glycosyl donors. Individual deoxyribozymes are each specific for a particular donor anomer.

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Foilsithe in:Chem Commun (Camb)
Main Authors: Hesser, Anthony R., Brandsen, Benjamin M., Walsh, Shannon M., Wang, Puzhou, Silverman, Scott K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945402/
https://ncbi.nlm.nih.gov/pubmed/27355482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc04329a
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