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Inhibition of proteolysis protects hippocampal neurons from ischemia.

Intense proteolysis of cytoskeletal proteins occurs in brain within minutes of transient ischemia, possibly because of the activation of calcium-sensitive proteases (calpains). This proteolytic event precedes overt signs of neuronal degeneration, is most pronounced in regions of selective neuronal v...

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Bibliografski detalji
Glavni autori: Lee, K S, Frank, S, Vanderklish, P, Arai, A, Lynch, G
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC52268/
https://ncbi.nlm.nih.gov/pubmed/1871130
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