Acute inhibition of TAK1 protects against neuronal death in cerebral ischemia

Neuronal apoptosis contributes to ischemic brain damage and neurodegenerative disorders. Key regulators of neuronal apoptosis are the transcription factor NF-κB and the MAP kinases p38/MAPK and JNK, which share a common upstream activator, the mitogen-activated protein kinase kinase kinase (MAP3K) T...

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Detalhes bibliográficos
Main Authors: Neubert, M, Ridder, D A, Bargiotas, P, Akira, S, Schwaninger, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178433/
https://ncbi.nlm.nih.gov/pubmed/21475303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.29
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