Acute inhibition of TAK1 protects against neuronal death in cerebral ischemia

Neuronal apoptosis contributes to ischemic brain damage and neurodegenerative disorders. Key regulators of neuronal apoptosis are the transcription factor NF-κB and the MAP kinases p38/MAPK and JNK, which share a common upstream activator, the mitogen-activated protein kinase kinase kinase (MAP3K) T...

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Bibliografske podrobnosti
Main Authors: Neubert, M, Ridder, D A, Bargiotas, P, Akira, S, Schwaninger, M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178433/
https://ncbi.nlm.nih.gov/pubmed/21475303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.29
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