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Acute inhibition of TAK1 protects against neuronal death in cerebral ischemia
Neuronal apoptosis contributes to ischemic brain damage and neurodegenerative disorders. Key regulators of neuronal apoptosis are the transcription factor NF-κB and the MAP kinases p38/MAPK and JNK, which share a common upstream activator, the mitogen-activated protein kinase kinase kinase (MAP3K) T...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3178433/ https://ncbi.nlm.nih.gov/pubmed/21475303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.29 |
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