Inhibition of proteolysis protects hippocampal neurons from ischemia.
Intense proteolysis of cytoskeletal proteins occurs in brain within minutes of transient ischemia, possibly because of the activation of calcium-sensitive proteases (calpains). This proteolytic event precedes overt signs of neuronal degeneration, is most pronounced in regions of selective neuronal v...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52268/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1871130/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7233 |
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