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hGBP-1 Expression Predicts Shorter Progression-Free Survival in Ovarian Cancers, While Contributing to Paclitaxel Resistance

Ovarian cancer is the gynecological cancer with the poorest prognosis. One significant reason is the development of resistance to the chemotherapeutic drugs used in its treatment. The large GTPase, hGBP-1, has been implicated in paclitaxel resistance in ovarian cell lines. Forced expression of hGBP-...

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Dettagli Bibliografici
Pubblicato in:J Cancer Ther
Autori principali: Wadi, Suzan, Tipton, Aaron R., Trendel, Jill A., Khuder, Sadik A., Vestal, Deborah J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226657/
https://ncbi.nlm.nih.gov/pubmed/28090373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/jct.2016.713097
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