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hGBP-1 Expression Predicts Shorter Progression-Free Survival in Ovarian Cancers, While Contributing to Paclitaxel Resistance

Ovarian cancer is the gynecological cancer with the poorest prognosis. One significant reason is the development of resistance to the chemotherapeutic drugs used in its treatment. The large GTPase, hGBP-1, has been implicated in paclitaxel resistance in ovarian cell lines. Forced expression of hGBP-...

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Detalhes bibliográficos
Publicado no:J Cancer Ther
Main Authors: Wadi, Suzan, Tipton, Aaron R., Trendel, Jill A., Khuder, Sadik A., Vestal, Deborah J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226657/
https://ncbi.nlm.nih.gov/pubmed/28090373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/jct.2016.713097
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