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The GTPase hGBP1 converts GTP to GMP in two steps via proton shuttle mechanisms
GTPases play a crucial role in the regulation of many biological processes by catalyzing the hydrolysis of GTP into GDP. The focus of this work is on the dynamin-related large GTPase human guanine nucleotide binding protein-1 (hGBP1) which is able to hydrolyze GTP even to GMP. Here, we studied the l...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5365056/ https://ncbi.nlm.nih.gov/pubmed/28451182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02045c |
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