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The GTPase hGBP1 converts GTP to GMP in two steps via proton shuttle mechanisms

GTPases play a crucial role in the regulation of many biological processes by catalyzing the hydrolysis of GTP into GDP. The focus of this work is on the dynamin-related large GTPase human guanine nucleotide binding protein-1 (hGBP1) which is able to hydrolyze GTP even to GMP. Here, we studied the l...

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Bibliografski detalji
Izdano u:Chem Sci
Glavni autori: Tripathi, Ravi, Glaves, Rachel, Marx, Dominik
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365056/
https://ncbi.nlm.nih.gov/pubmed/28451182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02045c
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