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Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks

Phosphorylation of histone H2AX on serine 139 (γH2AX) is an early step in cellular response to a DNA double-strand break (DSB). γH2AX foci are generally regarded as markers of DSBs. A growing body of evidence demonstrates, however, that while induction of DSBs always brings about phosphorylation of...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Rybak, Paulina, Hoang, Agnieszka, Bujnowicz, Lukasz, Bernas, Tytus, Berniak, Krzysztof, Zarębski, Mirosław, Darzynkiewicz, Zbigniew, Dobrucki, Jerzy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226530/
https://ncbi.nlm.nih.gov/pubmed/27391338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10411
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