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Analysis of Spatial Correlations Between Patterns of DNA Damage Response and DNA Replication in Nuclei of Cells Subjected to Replication Stress or Oxidative Damage

Sites of DNA replication (EdU incorporation) and DNA damage signaling (γH2AX) induced by camptothecin (Cpt) or hydrogen peroxide (H(2)O(2)) form characteristic patterns of foci in cell nuclei. The overlap between these patterns is a function of the number of DNA double strand breaks (DSBs) formed in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bernas, Tytus, Berniak, Krzysztof, Rybak, Paulina, Zarębski, Mirosław, Zhao, Hong, Darzynkiewicz, Zbigniew, Dobrucki, Jerzy W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907470/
https://ncbi.nlm.nih.gov/pubmed/23900967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.22325
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