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Analysis of Spatial Correlations Between Patterns of DNA Damage Response and DNA Replication in Nuclei of Cells Subjected to Replication Stress or Oxidative Damage
Sites of DNA replication (EdU incorporation) and DNA damage signaling (γH2AX) induced by camptothecin (Cpt) or hydrogen peroxide (H(2)O(2)) form characteristic patterns of foci in cell nuclei. The overlap between these patterns is a function of the number of DNA double strand breaks (DSBs) formed in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907470/ https://ncbi.nlm.nih.gov/pubmed/23900967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.22325 |
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