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An AlphaScreen Assay for the Discovery of Synthetic Chemical Inhibitors of Glucagon Production

Glucose homeostasis is primarily controlled by two opposing hormones, insulin and glucagon, and diabetes results when insulin fails to inhibit glucagon action. Recent efforts to control glucagon in diabetes have focused on antagonizing the glucagon receptor, which is effective in lowering blood gluc...

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Dades bibliogràfiques
Publicat a:J Biomol Screen
Autors principals: Evans, Matthew R., Wei, Shuguang, Posner, Bruce A., Unger, Roger H., Roth, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226228/
https://ncbi.nlm.nih.gov/pubmed/26676097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057115622201
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