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An AlphaScreen Assay for the Discovery of Synthetic Chemical Inhibitors of Glucagon Production

Glucose homeostasis is primarily controlled by two opposing hormones, insulin and glucagon, and diabetes results when insulin fails to inhibit glucagon action. Recent efforts to control glucagon in diabetes have focused on antagonizing the glucagon receptor, which is effective in lowering blood gluc...

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Detalhes bibliográficos
Publicado no:J Biomol Screen
Main Authors: Evans, Matthew R., Wei, Shuguang, Posner, Bruce A., Unger, Roger H., Roth, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226228/
https://ncbi.nlm.nih.gov/pubmed/26676097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057115622201
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