A Live Attenuated Chimeric West Nile Virus Vaccine, rWN/DEN4Δ30, Is Well Tolerated and Immunogenic in Flavivirus-Naive Older Adult Volunteers

West Nile virus (WNV) is a major cause of mosquito-borne illness in the United States. Human disease ranges from mild febrile illness to severe fatal neurologic infection. Adults aged >60 years are more susceptible to neuroinvasive disease accompanied by a high mortality rate or long-lasting neur...

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Pierce, Kristen K., Whitehead, Stephen S., Kirkpatrick, Beth D., Grier, Palmtama L., Jarvis, Adrienne, Kenney, Heather, Carmolli, Marya P., Reynolds, Cynthia, Tibery, Cecilia M., Lovchik, Janece, Janiak, Anna, Luke, Catherine J., Durbin, Anna P., Pletnev, Alexander G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225253/
https://ncbi.nlm.nih.gov/pubmed/28077583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw501
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