Robust and Balanced Immune Responses to All 4 Dengue Virus Serotypes Following Administration of a Single Dose of a Live Attenuated Tetravalent Dengue Vaccine to Healthy, Flavivirus-Naive Adults

Background. The 4 serotypes of dengue virus, DENV-1–4, are the leading cause of arboviral disease globally. The ideal dengue vaccine would provide protection against all serotypes after a single dose. Methods. Two randomized, placebo-controlled trials were performed with 168 flavivirus-naive adults...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Kirkpatrick, Beth D., Durbin, Anna P., Pierce, Kristen K., Carmolli, Marya P., Tibery, Cecilia M., Grier, Palmtama L., Hynes, Noreen, Diehl, Sean A., Elwood, Dan, Jarvis, Adrienne P., Sabundayo, Beulah P., Lyon, Caroline E., Larsson, Catherine J., Jo, Matthew, Lovchik, Janece M., Luke, Catherine J., Walsh, Mary C., Fraser, Ellen A., Subbarao, Kanta, Whitehead, Steven S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612392/
https://ncbi.nlm.nih.gov/pubmed/25801652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv082
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